Synthesis of water soluble undecagold clusters for specific labelling of 
proteins

Jahn, Werner

doi:10.1515/znb-1989-1027

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Synthesis of water soluble undecagold clusters for specific labelling of proteins

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Jahn, Werner
Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society;

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Citation

Jahn, W. (1989). Synthesis of water soluble undecagold clusters for specific labelling of proteins. Zeitschrift für Naturforschung, B: A Journal of Chemical Sciences, 44(10), 1313-1322. doi:10.1515/znb-1989-1027.

Cite as: https://hdl.handle.net/21.11116/0000-000B-5648-4

Abstract

A highly water soluble undecagold cluster was prepared using a N-hydroxyethyl-N-acetylderivative of 4,4',4"-phosphinidynetri(benzenem ethanam ine). Monofunctional clusters were synthesized in high yield by the exchange of ligands with phosphines having one free amino group.
The clusters can be used for heavy atom labelling of proteins after introduction of a reactive maleimido group.