Death and dessert: nutrient signalling pathways and ageing

Alic, N.; Partridge, L.

doi:S0955-0674(11)00100-1 [pii] 10.1016/j.ceb.2011.07.006

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Death and dessert: nutrient signalling pathways and ageing

MPS-Authors

/persons/resource/persons129348

Partridge, L.
Department Partridge - Biological Mechanisms of Ageing, Max Planck Institute for Biology of Ageing, Max Planck Society;

External Resource

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21835601
(Any fulltext)

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Alic, N., & Partridge, L. (2011). Death and dessert: nutrient signalling pathways and ageing. Curr Opin Cell Biol, 23(6), 738-43. doi:S0955-0674(11)00100-1 [pii] 10.1016/j.ceb.2011.07.006.

Cite as: https://hdl.handle.net/21.11116/0000-000B-B49C-A

Abstract

Reduction in nutrient intake without malnutrition can delay ageing and extend healthy life in diverse organisms from yeast to primates. This effect can be recapitulated by genetic or pharmacological dampening of the signal through nutrient signalling pathways, making them a promising target for intervention into human ageing and age-related diseases. Here we review the current knowledge of the interactions between nutrient signalling pathways and ageing, focusing on the findings emerged in the past few years.