Nuclear receptor signal transduction in C. elegans

Antebi, A.

doi:10.1895/wormbook.1.64.2

アイテム詳細

登録内容を編集ファイル形式で保存

一時保存へ追加

タグ情報を表示リリース履歴を表示詳細要約

公開

学術論文

Nuclear receptor signal transduction in C. elegans

MPS-Authors

/persons/resource/persons50070

Antebi, A.
Department Antebi - Molecular Genetics of Ageing, Max Planck Institute for Biology of Ageing, Max Planck Society;

External Resource

http://www.ncbi.nlm.nih.gov/pubmed/26069085
(全文テキスト（全般）)

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

フルテキスト (公開)

公開されているフルテキストはありません

付随資料 (公開)

There is no public supplementary material available

引用

Antebi, A. (2015). Nuclear receptor signal transduction in C. elegans. WormBook, 1-49. doi:10.1895/wormbook.1.64.2.

引用: https://hdl.handle.net/21.11116/0000-000B-B3F7-4

要旨

Nuclear receptors are transcription factors that often respond to small molecule metabolites and fat-soluble compounds to regulate gene expression. They broadly govern development, reproduction, metabolism, and homeostasis in diverse metazoan species and their dysregulation is associated with numerous diseases. Work in C. elegans has shed light on the seminal role of nuclear receptors in life history regulation, stem cell progression, developmental timing, cell fate specification, nutrient sensing, metabolism, and longevity. Here we highlight recent advances on the best-studied nuclear receptors in the worm, and how they illuminate metazoan biology.