Structure casts light on mtDNA replication

Falkenberg, M.; Larsson, N.G.

doi:10.1016/j.cell.2009.09.030

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Structure casts light on mtDNA replication

MPS-Authors

/persons/resource/persons129342

Larsson, N.G.
Department Larsson - Mitochondrial Biology, Max Planck Institute for Biology of Ageing, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Falkenberg, M., & Larsson, N. (2009). Structure casts light on mtDNA replication. Cell, 139(2), 231-3. doi:10.1016/j.cell.2009.09.030.

Cite as: https://hdl.handle.net/21.11116/0000-000B-9DBD-0

Abstract

In this issue, Lee et al. (2009) present a crystal structure of the human mitochondrial DNA polymerase (POLgamma). The structure of this heterotrimeric enzyme lays a foundation for understanding how POLgamma mutations cause human mitochondrial disease and why some antiviral nucleoside analogs cause cellular toxicity.