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A dividing matter: Drp1/Dnm1-independent mitophagy

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Graef,  M.
Graef – Autophagy and Cellular Ageing, Max Planck Research Groups, Max Planck Institute for Biology of Ageing, Max Planck Society;

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Citation

Graef, M. (2016). A dividing matter: Drp1/Dnm1-independent mitophagy. J Cell Biol, 215(5), 599-601. doi:10.1083/jcb.201611079.


Cite as: https://hdl.handle.net/21.11116/0000-000B-718D-7
Abstract
Whether or not mitophagy depends on prior mitochondrial fragmentation by the canonical mitochondrial division machinery is controversial. In this issue, Yamashita et al. (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201605093) report that mitochondrial fragments start to bud and divide from mitochondrial tubules when in tight association with forming autophagosomes, but independently of the mitochondrial division factor Drp1/Dnm1.