MTERF1 gives mtDNA an unusual twist

Gustafsson, C. M.; Larsson, N.G.

doi:10.1016/j.cmet.2010.06.006

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MTERF1 gives mtDNA an unusual twist

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Larsson, N.G.
Department Larsson - Mitochondrial Biology, Max Planck Institute for Biology of Ageing, Max Planck Society;

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Gustafsson, C. M., & Larsson, N. (2010). MTERF1 gives mtDNA an unusual twist. Cell Metab, 12(1), 3-4. doi:10.1016/j.cmet.2010.06.006.

Cite as: https://hdl.handle.net/21.11116/0000-000B-9D61-7

Abstract

Expression of mtDNA is critical for biogenesis of the oxidative phosphorylation system, but the regulatory processes are poorly understood. Recent work in Cell (Yakubovskaya et al., 2010) reports a novel DNA-binding fold in mitochondrial transcription termination factor 1 (MTERF1), which causes unwinding and base eversion at its target mtDNA sequence.