A family of putative transcription termination factors shared amongst metazoans 
and plants

Linder, T.; Park, C. B.; Asin-Cayuela, J.; Pellegrini, M.; Larsson, N.G.; Falkenberg, M.; Samuelsson, T.; Gustafsson, C. M.

doi:10.1007/s00294-005-0022-5

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A family of putative transcription termination factors shared amongst metazoans and plants

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Larsson, N.G.
Department Larsson - Mitochondrial Biology, Max Planck Institute for Biology of Ageing, Max Planck Society;

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Citation

Linder, T., Park, C. B., Asin-Cayuela, J., Pellegrini, M., Larsson, N., Falkenberg, M., et al. (2005). A family of putative transcription termination factors shared amongst metazoans and plants. Curr Genet, 48(4), 265-9. doi:10.1007/s00294-005-0022-5.

Cite as: https://hdl.handle.net/21.11116/0000-000B-7484-D

Abstract

The human mitochondrial transcription termination factor (mTERF) is involved in the regulation of transcription of the mitochondrial genome. Similarity searches and phylogenetic analysis demonstrate that mTERF is a member of large and complex protein family (the MTERF family) shared amongst metazoans and plants. Interestingly, we identify three novel MTERF genes in vertebrates, which all encode proteins with predicted mitochondrial localization. Members of the MTERF family have so far not been detected in fungi, supporting the notion that mitochondrial transcription regulation may have evolved separately in yeast and animal cells.