Protocols to Study Aging in Drosophila

Piper, M. D.; Partridge, L.

doi:10.1007/978-1-4939-6371-3_18

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Protocols to Study Aging in Drosophila

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Partridge, L.
Department Partridge - Biological Mechanisms of Ageing, Max Planck Institute for Biology of Ageing, Max Planck Society;

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https://www.ncbi.nlm.nih.gov/pubmed/27730590
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Piper, M. D., & Partridge, L. (2016). Protocols to Study Aging in Drosophila. Methods Mol Biol, 1478, 291-302. doi:10.1007/978-1-4939-6371-3_18.

Cite as: https://hdl.handle.net/21.11116/0000-000B-7448-2

Abstract

The fruit fly Drosophila melanogaster offers a host of advantages for studying the biology of aging: a well-understood biology, a wide range of genetic reagents, well-defined dietary requirements, and a relatively short life span, with a median of ~80 days and maximum ~100 days. Several phenotypes can be used to assess the aging process, but the simplest and most widely used metric is length of life. Here we describe a standard life span assay for Drosophila housed on a simple sugar/yeast diet.