AAA proteases in mitochondria: diverse functions of membrane-bound proteolytic 
machines

Tatsuta, T.; Langer, T.

doi:10.1016/j.resmic.2009.09.005

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AAA proteases in mitochondria: diverse functions of membrane-bound proteolytic machines

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Tatsuta, T.
Department Langer - Mitochondrial Proteostasis, Max Planck Institute for Biology of Ageing, Max Planck Society;

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Langer, T.
Department Langer - Mitochondrial Proteostasis, Max Planck Institute for Biology of Ageing, Max Planck Society;

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https://www.ncbi.nlm.nih.gov/pubmed/19781639
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Citation

Tatsuta, T., & Langer, T. (2009). AAA proteases in mitochondria: diverse functions of membrane-bound proteolytic machines. Res Microbiol, 160(9), 711-7. doi:10.1016/j.resmic.2009.09.005.

Cite as: https://hdl.handle.net/21.11116/0000-000B-6E64-A

Abstract

FtsH/AAA proteases comprise a distinct family of membrane-bound, ATP-dependent proteases present in eubacteria and eukaryotic cells, where they are confined to mitochondria and chloroplasts. Here, we will summarize versatile functions of AAA proteases within mitochondria, which ensure mitochondrial integrity and cell survival, acting both as quality control and processing enzymes.