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Information for the dorsal-ventral pattern of the Drosophila embryo is stored as maternal mRNA

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Anderson,  KV
Nüsslein-Volhard Group, Friedrich Miescher Laboratory, Max Planck Society;

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Nüsslein-Volhard,  C       
Nüsslein-Volhard Group, Friedrich Miescher Laboratory, Max Planck Society;

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Citation

Anderson, K., & Nüsslein-Volhard, C. (1984). Information for the dorsal-ventral pattern of the Drosophila embryo is stored as maternal mRNA. Nature, 311(5983), 223-227. doi:10.1038/311223a0.


Cite as: https://hdl.handle.net/21.11116/0000-000B-6A5B-9
Abstract
Maternal-effect mutations in 10 loci in Drosophila produce totally 'dorsalized' embryos. Injection of RNA isolated from wild-type embryos into mutants at six loci partially restores dorsal-ventral polarity. For the mutant snake, injection of poly(A)+ RNA restores a complete dorsal-ventral pattern.