The bicoid protein is a positive regulator of hunchback transcription in the 
early Drosophila embryo

Driever, W; Nüsslein-Volhard, C

doi:10.1038/337138a0

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The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo

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Driever, W
Department Genetics, Max Planck Institute for Developmental Biology, Max Planck Society;

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Nüsslein-Volhard, C
Department Genetics, Max Planck Institute for Developmental Biology, Max Planck Society;

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Citation

Driever, W., & Nüsslein-Volhard, C. (1989). The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo. Nature, 337(6203), 138-143. doi:10.1038/337138a0.

Cite as: https://hdl.handle.net/21.11116/0000-000B-6B08-5

Abstract

A gradient in concentration of the protein product of the bicoid gene is a determinant of the anterior-posterior axis of Drosophila embryos. By binding upstream of the segmentation gene hunchback the bicoid protein controls its transcription, thereby translating maternal pattern-generating information into differential activation of zygotic gene expression.