Ionic specificity of the gramicidin channel and the thallous ion

Neher, Erwin

doi:10.1016/0005-2736(75)90252-7

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Ionic specificity of the gramicidin channel and the thallous ion

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Neher, Erwin
Department of Membrane Biophysics, MPI for biophysical chemistry, Max Planck Society;

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Citation

Neher, E. (1975). Ionic specificity of the gramicidin channel and the thallous ion. Biochimica et Biophysica Acta: BBA, 401(3), 540-544. doi:10.1016/0005-2736(75)90252-7.

Cite as: https://hdl.handle.net/21.11116/0000-000B-7618-6

Abstract

The thallous ion was found to interact very specifically with gramicidin channels in black lipid membranes. Although the ion itself carries current through the channel better than Na⁺ or K⁺, it blocks Na⁺ currents at concentrations which are two orders of magnitude lower than the Na⁺ concentrations.