Ni-Catalyzed Oxygen Transfer from N2O onto sp3-Hybridized Carbons

Ni, Shengyang; Le Vaillant, Franck; Mateos-Calbet, Ana; Martin, Ruben; Cornella, Josep

doi:10.1021/jacs.2c06227

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Ni-Catalyzed Oxygen Transfer from N₂O onto sp³-Hybridized Carbons

MPS-Authors

/persons/resource/persons264922

Ni, Shengyang
Research Group Cornellà, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons255312

Le Vaillant, Franck
Research Group Cornellà, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons273670

Mateos-Calbet, Ana
Research Group Cornellà, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons207433

Cornella, Josep
Research Group Cornellà, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Ni, S., Le Vaillant, F., Mateos-Calbet, A., Martin, R., & Cornella, J. (2022). Ni-Catalyzed Oxygen Transfer from N₂O onto sp³-Hybridized Carbons. Journal of the American Chemical Society, 144(40), 18223-18228. doi:10.1021/jacs.2c06227.

Cite as: https://hdl.handle.net/21.11116/0000-000B-9BAE-3

Abstract

Herein we disclose a catalytic synthesis of cycloalkanols that harnesses the potential of N₂O as an oxygen transfer agent onto sp³-hybridized carbons. The protocol is distinguished by its mild conditions and wide substrate scope, thus offering an opportunity to access carbocyclic compounds from simple precursors even in an enantioselective manner. Preliminary mechanistic studies suggest that the oxygen insertion event occurs at an alkylnickel species and that N₂O is the O transfer reagent.