MetaScope: Fast and accurate identification of microbes in metagenomic 
sequencing data

Buchfink, B; Huson, DH; Xie, C

doi:10.48550/arXiv.1511.08753

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MetaScope: Fast and accurate identification of microbes in metagenomic sequencing data

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Buchfink, B., Huson, D., & Xie, C. (submitted). MetaScope: Fast and accurate identification of microbes in metagenomic sequencing data.

Cite as: https://hdl.handle.net/21.11116/0000-000C-3EF8-8

Abstract

MetaScope is a fast and accurate tool for analyzing (host-associated) metagenome datasets. Sequence alignment of reads against the host genome (if requested) and against microbial Genbank is performed using a new DNA aligner called SASS. The output of SASS is processed so as to assign all microbial reads to taxa and genes, using a new weighted version of the LCA algorithm. MetaScope is the winner of the 2013 DTRA software challenge entitled "Identify Organisms from a Stream of DNA Sequences".