Tumor antigen induction by the envelope-defective Bryan strain of Rous sarcoma 
viruses

Kurth, R; Kitchener, G

doi:10.1093/jnci/60.6.1365

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Tumor antigen induction by the envelope-defective Bryan strain of Rous sarcoma viruses

MPS-Authors

/persons/resource/persons286225

Kurth, R
Kurth Group, Friedrich Miescher Laboratory, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Kurth, R., & Kitchener, G. (1978). Tumor antigen induction by the envelope-defective Bryan strain of Rous sarcoma viruses. Journal of the National Cancer Institute, 60(6), 1365-1369. doi:10.1093/jnci/60.6.1365.

Cite as: https://hdl.handle.net/21.11116/0000-000C-898A-E

Abstract

Chicken, quail, and turkey cells were infected and/or transformed by various avian leukosis or sarcoma oncovirus (ALSV) strains as well as by the envelope-defective Bryan high-titer strain of Rous sarcoma virus [BH-RSV(-)]. All fibroblast-transforming avian sarcoma viruses (ASV), including BH-RSV(-), were able to induce the expression of the previously described avian tumor-specific cell-surface antigen(s) (TSSA). Thus TSSA was group-specific for all tested transforming ASV. Since BH-RSV(-) is a stable deletion mutant lacking the capacity to code for the 85 000d major virus envelope glycoprotein (gp85), it seemed unlikely that the group-specific antigen determinants of gp85 that were recently detected on ALSV-infected cells could account for TSSA expression.