Structural Organization of Unique Retrovirus-like Particles Budding from Human 
Teratocarcinoma Cell Lines

Boller, K; Frank, H; Löwer, J; Löwer, R; Kurth, R

doi:10.1099/0022-1317-64-12-2549

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Structural Organization of Unique Retrovirus-like Particles Budding from Human Teratocarcinoma Cell Lines

MPS-Authors

/persons/resource/persons286534

Löwer, R
Kurth Group, Friedrich Miescher Laboratory, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Boller, K., Frank, H., Löwer, J., Löwer, R., & Kurth, R. (1983). Structural Organization of Unique Retrovirus-like Particles Budding from Human Teratocarcinoma Cell Lines. Journal of General Virology, 64(12), 2549-2559. doi:10.1099/0022-1317-64-12-2549.

Cite as: https://hdl.handle.net/21.11116/0000-000C-90B1-8

Abstract

Human teratocarcinoma cells cultured in vitro can be induced to produce retrovirus-like particles. The induction procedures are the same as those previously shown to induce the synthesis of animal retroviruses. Electron microscopical evidence is presented that the human teratocarcinoma-derived (HTD) particles are most closely related to the type C retrovirus strains. HTD particles can be banded at 1.16 g/ml in linear sucrose gradients, the characteristic density for retroviruses, and subsequently be used for negative staining and fine structure analysis.