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Journal Article

Therapies for obsessive-compulsive disorder: Current state of the art and perspectives for approaching treatment-resistant patients

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Draganski,  Bogdan
Département des Neurosciences Cliniques, Laboratoire de Recherche en Neuroimagerie (LREN), Centre hospitalier universitaire vaudois, Lausanne, Switzerland;
Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Citation

Swierkosz-Lenart, K., Dos Santos, J. F. A., Elowe, J., Clair, A.-H., Bally, J. F., Riquier, F., et al. (2023). Therapies for obsessive-compulsive disorder: Current state of the art and perspectives for approaching treatment-resistant patients. Frontiers in Psychiatry, 14: 1065812. doi:10.3389/fpsyt.2023.1065812.


Cite as: https://hdl.handle.net/21.11116/0000-000C-BC99-4
Abstract
Even though obsessive compulsive disorder (OCD) is one of the ten most disabling diseases according to the WHO, only 30-40% of patients suffering from OCD seek specialized treatment. The currently available psychotherapeutic and pharmacological approaches, when properly applied, prove ineffective in about 10% of cases. The use of neuromodulation techniques, especially Deep Brain Stimulation, is highly promising for these clinical pictures and knowledge in this domain is constantly evolving. The aim of this paper is to provide a summary of the current knowledge about OCD treatment, while also discussing the more recent proposals for defining resistance.