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Automated glycan assembly of highly branched heptadecasaccharide repeating unit of arabinogalactan polysaccharide HH1-1 from Carthamus tinctorius

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Sabbavarapu,  Narayana Murthy       
Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Seeberger,  Peter H.       
Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Zitation

Sabbavarapu, N. M., & Seeberger, P. H. (2023). Automated glycan assembly of highly branched heptadecasaccharide repeating unit of arabinogalactan polysaccharide HH1-1 from Carthamus tinctorius. Chemical Communications, 59(32), 4822-4824. doi:10.1039/D3CC00687E.


Zitierlink: https://hdl.handle.net/21.11116/0000-000C-E03A-6
Zusammenfassung
Polysaccharides that are part of the human diet of fruits and vegetables influence the immune system via multiple signaling pathways. Given the immense complexity and diversity of naturally occurring polysaccharides and the difficulties associated isolating pure samples, few structure-activity relationships have been established. Rapid access to well-defined polysaccharides of biological relevance by automated glycan assembly (AGA) is important to create chemical tools to determine the link between nutritional oligo- and polysaccharides and the immune response. Here, we describe AGA of a hyper branched heptadecasaccharide repeating unit of arabinogalactan polysaccharide HH1-1 from Carthamus tinctorius.