English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
  Local TagsRelease HistoryDetailsSummary

Released
Journal Article

Revisiting the focality of non-invasive brain stimulation - implications for studies of human cognition

MPS-Authors

Numssen,  Ole
Lise Meitner Research Group Cognition and Plasticity, MPI for Human Cognitive and Brain Sciences, Max Planck Society;
Methods and Development Group Brain Networks, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

/persons/resource/persons182532

van der Burght,  Constantijn L.       
Psychology of Language Department, MPI for Psycholinguistics, Max Planck Society;

Hartwigsen,  Gesa
Lise Meitner Research Group Cognition and Plasticity, MPI for Human Cognitive and Brain Sciences, Max Planck Society;
Wilhelm Wundt Institute for Psychology, Leipzig University;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
Supplementary Material (public)
There is no public supplementary material available
Citation

Numssen, O., van der Burght, C. L., & Hartwigsen, G. (2023). Revisiting the focality of non-invasive brain stimulation - implications for studies of human cognition. Neuroscience and Biobehavioral Reviews, 149: 105154. doi:10.1016/j.neubiorev.2023.105154.


Cite as: https://hdl.handle.net/21.11116/0000-000C-E073-5
Abstract
Non-invasive brain stimulation techniques are popular tools to investigate brain function in health and disease. Although transcranial magnetic stimulation (TMS) is widely used in cognitive neuroscience research to probe causal structure-function relationships, studies often yield inconclusive results. To improve the effectiveness of TMS studies, we argue that the cognitive neuroscience community needs to revise the stimulation focality principle – the spatial resolution with which TMS can differentially stimulate cortical regions. In the motor domain, TMS can differentiate between cortical muscle representations of adjacent fingers. However, this high degree of spatial specificity cannot be obtained in all cortical regions due to the influences of cortical folding patterns on the TMS-induced electric field. The region-dependent focality of TMS should be assessed a priori to estimate the experimental feasibility. Post-hoc simulations allow modeling of the relationship between cortical stimulation exposure and behavioral modulation by integrating data across stimulation sites or subjects.