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Journal Article

Luminescent DNA-origami nano-rods dispersed in a lyotropic chromonic liquid crystal


Heuer-Jungemann,  Amelie
Amelie Heuer-Jungemann / DNA Hybridnanomaterials, Max Planck Institute of Biochemistry, Max Planck Society;

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Zhang, B., Nguyen, L., Martens, K., Heuer-Jungemann, A., Philipp, J., Kempter, S., et al. (2023). Luminescent DNA-origami nano-rods dispersed in a lyotropic chromonic liquid crystal. Liquid Crystals. doi:10.1080/02678292.2023.2188494.

Cite as: https://hdl.handle.net/21.11116/0000-000D-1171-0
Anisometric DNA nanoparticles with precisely tailored size and shape are prepared by three-dimensional folding of DNA - DNA origami - marked with a fluorescent intercalating dye (YOYO-1), stabilised with silica, and dispersed in a lyotropic chromonic liquid crystal (an aqueous solution of disodium cromoglycate). Observations by total internal reflection fluorescence microscopy indicate that the luminescent nanoparticles are stable in the liquid crystal dispersion and accumulate at the positions of point defects in the liquid crystal director field. The observations indicate that silica-stabilisation of the nanoparticles prevents the dye from leaking into the liquid crystal host and that the luminescent particles assemble at disclinations.