Pharmacological analysis of cortical circuitry

Bolz, J; Gilbert, CD; Wiesel, TN

doi:10.1016/0166-2236(89)90009-x

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Pharmacological analysis of cortical circuitry

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Bolz, J
Bolz Group, Friedrich Miescher Laboratory, Max Planck Society;

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Citation

Bolz, J., Gilbert, C., & Wiesel, T. (1989). Pharmacological analysis of cortical circuitry. Trends in Neurosciences, 12(8), 292-296. doi:10.1016/0166-2236(89)90009-x.

Cite as: https://hdl.handle.net/21.11116/0000-000D-1345-0

Abstract

The cortical circuitry of the visual cortex has been worked out in great detail. Anatomical investigations reveal stereotyped connections within cortical columns and specific long-range connections between distant columns. Pharmacological techniques for blocking the activity in individual cortical layers or columns allow the microdissection of the cortical circuit. These studies could relate specific functional roles to particular cortical connections.