Modified Hebbian Rule for Synaptic Enhancement in the Hippocampus and the 
Visual Cortex

Bonhoeffer, T; Kossel, A; Bolz, J; Aertsen, A

doi:10.1101/SQB.1990.055.01.017

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Modified Hebbian Rule for Synaptic Enhancement in the Hippocampus and the Visual Cortex

MPS-Authors

/persons/resource/persons38941

Kossel, A
Bolz Group, Friedrich Miescher Laboratory, Max Planck Society;

/persons/resource/persons282645

Bolz, J
Bolz Group, Friedrich Miescher Laboratory, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Bonhoeffer, T., Kossel, A., Bolz, J., & Aertsen, A. (1990). Modified Hebbian Rule for Synaptic Enhancement in the Hippocampus and the Visual Cortex. Cold Spring Harbor Symposia on Quantitative Biology, 55, 137-146. doi:10.1101/SQB.1990.055.01.017.

Cite as: https://hdl.handle.net/21.11116/0000-000D-1348-D

Abstract

Ramón y Cajal (1909, 1911) was the first to suggest that synapses might be the locations at which memory is laid down in the brain. Some 50 years later, Donald Hebb proposed the physiological condition under which this might happen (Hebb 1949). He invoked the notion of “synaptic plasticity”: Activity occurring simultaneously at the neurons pre- and postsynaptic to a particular synapse would lead to an increase in the efficacy of that synapse. This postulate later became known as the Hebb rule and was widely adopted by both experimentors and theoreticians. Hebb's model of synaptic plasticity provided a natural explanation for many experimental observations on learning, memory, and development.