Sensitive electrochemical detection of superoxide anion using gold 
nanoparticles distributed poly(methyl methacrylate)-polyaniline core-shell 
electrospun composite electrode

Santhosh, P.; Manesh, K. M.; Lee, S. H.; Uthayakumar, S.; Gopalan, A. I.; Lee, K. P.

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Sensitive electrochemical detection of superoxide anion using gold nanoparticles distributed poly(methyl methacrylate)-polyaniline core-shell electrospun composite electrode

MPS-Authors

Uthayakumar, S.
Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Santhosh, P., Manesh, K. M., Lee, S. H., Uthayakumar, S., Gopalan, A. I., & Lee, K. P. (2011). Sensitive electrochemical detection of superoxide anion using gold nanoparticles distributed poly(methyl methacrylate)-polyaniline core-shell electrospun composite electrode. Analyst, 136(8), 1557-1561.

Cite as: https://hdl.handle.net/21.11116/0000-000E-BED5-C

Abstract

In the present communication, a novel composite nanofibrous electrode is developed for the detection of superoxide anion (O(2)(.-)) in phosphate buffered saline (PBS). The composite fiber electrode is fabricated by dispersing gold nanoparticles onto poly(methyl methacrylate) (PMMA)-polyaniline (PANI) core-shell electrospun nanofibers. The constructed architecture is proven to be a favorable environment for the immobilization of the enzyme, superoxide dismutase (SOD). Direct electron transfer is achieved between SOD and the electrode with an electron transfer rate constant of 8.93 s(-1). At an applied potential of +300 mV, PMMA/PANI-Au(nano)/SOD-ESCFM shows highly sensitive detection of O(2)(.-). In addition to this, quantification of different activities of SOD is realized at PMMA/PANI-Au(nano)/SOD-ESCFM. These analytical features offer great potential for construction of the third-generation O(2)(.-) biosensor.