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Chasing cortical behavior: designing multiphoton microscopes for imaging neuronal populations in freely moving rodents

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Klioutchnikov,  Alexandr
Department of Behavior and Brain Organization, Max Planck Institute for Neurobiology of Behavior – caesar, Max Planck Society;

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Kerr,  Jason N. D.       
Department of Behavior and Brain Organization, Max Planck Institute for Neurobiology of Behavior – caesar, Max Planck Society;

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Citation

Klioutchnikov, A., & Kerr, J. N. D. (2023). Chasing cortical behavior: designing multiphoton microscopes for imaging neuronal populations in freely moving rodents. Neurophotonics, 10(4): 044411. doi:10.1117/1.NPh.10.4.044411.


Cite as: https://hdl.handle.net/21.11116/0000-000D-DE4E-3
Abstract
Imaging in the freely moving animal gives unparalleled access to circuit activity as the animal interacts with its environment in a self-guided way. Over the past few years, new imaging technologies have enabled the interrogation of neuronal populations located at any depth of the cortex in freely moving mice while preserving the animal’s behavioral repertoire. This commentary gives an updated overview of the recent advances that have enabled the link between behavior and the underlying neuronal activity to be explored.