Help Privacy Policy Disclaimer
  Advanced SearchBrowse




Journal Article

Caged lipid probes for controlling lipid levels on subcellular scales.


Nadler,  André
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available

Jiménez-López, C., & Nadler, A. (2023). Caged lipid probes for controlling lipid levels on subcellular scales. Current opinion in chemical biology, 72: 102234. doi:10.1016/j.cbpa.2022.102234.

Cite as: https://hdl.handle.net/21.11116/0000-000E-AAAE-F
Lipids exert their cellular functions in individual organelles, in some cases on the scale of even smaller, specialized membrane domains. Thus, the experimental capacity to precisely manipulate lipid levels at the subcellular level is crucial for studying lipid-related processes in cell biology. Photo-caged lipid probes which partition into specific cellular membranes prior to photoactivation have emerged as key tools for localized and selective perturbation of lipid concentration in living cells. In this review, we provide an overview of the recent advances in the area and outline which developments are still required for the methodology to be more widely implemented in the wider membrane biology community.