Live-bearing cockroach genome reveals convergent evolutionary mechanisms linked 
to viviparity in insects and beyond.

Fouks, Bertrand; Harrison, Mark C; Mikhailova, Alina A; Marchal, Elisabeth; English, Sinead; Carruthers, Madeleine; Jennings, Emily C; Chiamaka, Ezemuoka L; Frigard, Ronja A; Pippel, Martin; Attardo, Geoffrey M; Benoit, Joshua B; Bornberg-Bauer, Erich; Tobe, Stephen S

doi:10.1016/j.isci.2023.107832

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Live-bearing cockroach genome reveals convergent evolutionary mechanisms linked to viviparity in insects and beyond.

MPS-Authors

/persons/resource/persons246904

Pippel, Martin
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Fouks, B., Harrison, M. C., Mikhailova, A. A., Marchal, E., English, S., Carruthers, M., et al. (2023). Live-bearing cockroach genome reveals convergent evolutionary mechanisms linked to viviparity in insects and beyond. iScience, 26(10): 107832. doi:10.1016/j.isci.2023.107832.

Cite as: https://hdl.handle.net/21.11116/0000-000E-AB08-9

Abstract

Live birth (viviparity) has arisen repeatedly and independently among animals. We sequenced the genome and transcriptome of the viviparous Pacific beetle-mimic cockroach and performed comparative analyses with two other viviparous insect lineages, tsetse flies and aphids, to unravel the basis underlying the transition to viviparity in insects. We identified pathways undergoing adaptive evolution for insects, involved in urogenital remodeling, tracheal system, heart development, and nutrient metabolism. Transcriptomic analysis of cockroach and tsetse flies revealed that uterine remodeling and nutrient production are increased and the immune response is altered during pregnancy, facilitating structural and physiological changes to accommodate and nourish the progeny. These patterns of convergent evolution of viviparity among insects, together with similar adaptive mechanisms identified among vertebrates, highlight that the transition to viviparity requires changes in urogenital remodeling, enhanced tracheal and heart development (corresponding to angiogenesis in vertebrates), altered nutrient metabolism, and shifted immunity in animal systems.