Brain rhythms for bottom-up and top-down signaling

Fries, P

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Brain rhythms for bottom-up and top-down signaling

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Fries, P
Department of Computational Neuroscience, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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https://pnc.unipd.it/brain-rhythms-for-bottom-up-and-top-down-signaling-2/
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Citation

Fries, P. (2024). Brain rhythms for bottom-up and top-down signaling. Talk presented at Università degli Studi di Padova: Padova Neuroscience Center. Padova, Italy. 2024-05-16.

Cite as: https://hdl.handle.net/21.11116/0000-000F-63ED-7

Abstract

Brain networks typically engage in rhythmic synchronization, and this might serve functions, e.g. the processing of stimuli. I will show that repeated visual stimuli induce decreasing firing rates yet enhanced gamma-band synchronization, likely to maintain postsynaptic impact. This impact is indeed optimal for gamma-rhythmic inputs, as I will show by controlling inputs with optogenetics. Optogenetics can also be used to control top-down inputs. I will show that this Opto-Top-Down induces strong, up to several fold, changes in gamma-band synchronization together with much smaller changes in firing rate and no correlation between the two effects.