Head and tail development of the Drosophila embryo involves spalt, a novel 
homeotic gene

Jürgens, G

doi:10.1002/j.1460-2075.1988.tb02799.x

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Head and tail development of the Drosophila embryo involves spalt, a novel homeotic gene

MPS-Authors

/persons/resource/persons271466

Jürgens, G
Department Genetics, Max Planck Institute for Developmental Biology, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Jürgens, G. (1988). Head and tail development of the Drosophila embryo involves spalt, a novel homeotic gene. The EMBO Journal, 7(1), 189-196. doi:10.1002/j.1460-2075.1988.tb02799.x.

Cite as: https://hdl.handle.net/21.11116/0000-000F-8022-9

Abstract

Mutations in spalt (sal), a novel homeotic gene on the second chromosome of Drosophila, cause opposite transformations in two subterminal regions of the embryo: posterior head segments are transformed into anterior thoracic structures and anterior tail segments are transformed into posterior abdominal structures. The embryonic phenotypes of double mutants for sal and various Antennapedia (ANT-C) or bithorax (BX-C) genes indicate that sal acts independently of the hierarchical order of the latter gene complexes. Trans-regulatory gene mutations causing ectopic expression of ANT-C and BX-C genes do not change the realms of sal action. It is proposed that the region-specific action of the sal gene primarily promotes head as opposed to trunk development, while the BX-C gene AbdB distinguishes tail from head.