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Journal Article

Mps1 checks up on chromosome attachment

MPS-Authors
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Hauf,  S       
Hauf Group, Friedrich Miescher Laboratory, Max Planck Society;

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Citation

Hauf, S. (2008). Mps1 checks up on chromosome attachment. Cell, 132(2), 181-182. doi:10.1016/j.cell.2008.01.008.


Cite as: https://hdl.handle.net/21.11116/0000-000F-856E-0
Abstract
The protein kinase Mps1, a crucial regulator of the spindle-assembly checkpoint, now turns out to be essential for correcting errors in chromosome attachment (Jelluma et al., 2008). Mps1 exerts this effect by regulating the activity of the Aurora B kinase through phosphorylation of its partner protein Borealin.