English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Thermally Assisted Microfluidics to Produce Chemically Equivalent Microgels with Tunable Network Morphologies

MPS-Authors
/persons/resource/persons256228

Kim,  Kyoohyun
Guck Division, Max Planck Institute for the Science of Light, Max Planck Society;

/persons/resource/persons241284

Guck,  Jochen
Guck Division, Max Planck Institute for the Science of Light, Max Planck Society;
Guck Division, Max-Planck-Zentrum für Physik und Medizin, Max Planck Institute for the Science of Light, Max Planck Society;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)

Angew Chem Int Ed 2024 Rommel.pdf
(Publisher version), 2MB

Supplementary Material (public)
There is no public supplementary material available
Citation

Rommel, D., Häßel, B., Pietryszek, P., Mork, M., Jung, O., Emondts, M., et al. (2025). Thermally Assisted Microfluidics to Produce Chemically Equivalent Microgels with Tunable Network Morphologies. Angewandte Chemie, International Edition in English, 64(1). doi:10.1002/anie.202411772.


Cite as: https://hdl.handle.net/21.11116/0000-0010-03D0-F
Abstract
Although micron-sized microgels have become important building blocks in regenerative materials, offering decisive interactions with living matter, their chemical composition mostly significantly varies when their network morphology is tuned. Since cell behavior is simultaneously affected by the physical, chemical, and structural properties of the gel network, microgels with variable morphology but chemical equivalence are of interest. This work describes a new method to produce thermoresponsive microgels with defined mechanical properties, surface morphologies, and volume phase transition temperatures. A wide variety of microgels is synthesized by crosslinking monomers or star polymers at different temperatures using thermally assisted microfluidics. The diversification of microgels with different network structures and morphologies but of chemical equivalence offers a new platform of microgel building blocks with the ability to undergo phase transition at physiological temperatures. The method holds high potential to create soft and dynamic materials while maintaining the chemical composition for a wide variety of applications in biomedicine.