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Domestication and Innovation: Half a billion years of vertebrate immunity

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Boehm,  T       
Evolution of Adaptive Immunity in Vertebrates, Max Planck Institute for Biology Tübingen, Max Planck Society;

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Citation

Boehm, T. (2025). Domestication and Innovation: Half a billion years of vertebrate immunity. Talk presented at Distinguished Speaker Seminar Series (DSSS). Tübingen, Germany. 2025-01-10.


Cite as: https://hdl.handle.net/21.11116/0000-0010-6AEB-F
Abstract
Revolutionary advances in cellular and molecular biology, genomics and methods of genetic modification now offer unprecedented opportunities to consider, at unprecedented scale, the impact of the astounding phenotypic diversity of vertebrates on immune system function. Using a broad range of model and non-model organisms, we seek to understand how innate and adaptive immunity work together to ensure tissue homeostasis and to coordinate the fight against infections. We expect that the emerging general principles and the discovery of their evolutionarily selected variations will inspire the future development of novel therapeutic strategies for human immune disorders.