English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A

MPS-Authors
/persons/resource/persons4015

Li,  A. Y.
Department of Bioorganic Chemistry, MPI for Chemical Ecology, Max Planck Society;

/persons/resource/persons4095

Piel,  J.
Department of Bioorganic Chemistry, MPI for Chemical Ecology, Max Planck Society;

Locator
There are no locators available
Fulltext (public)
There are no public fulltexts available
Supplementary Material (public)
There is no public supplementary material available
Citation

Li, A. Y., & Piel, J. (2002). A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A. Chemistry and Biology, 9(9), 1017-1026.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0012-A198-7
Abstract
The telomerase inhibitor griseorhodin A is probably the most heavily oxidized bacterial polyketide known and features a unique epoxyspiroketal moiety crucial for its activity. To gain insight into which tailoring enzymes generate this pharmacophore, we