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Unprecedented diversity of catalytic domains in the first four modules of the putative pederin polyketide synthase

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Piel,  J.
Department of Bioorganic Chemistry, MPI for Chemical Ecology, Max Planck Society;

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Hui,  D. Q.
Department of Bioorganic Chemistry, MPI for Chemical Ecology, Max Planck Society;

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Citation

Piel, J., Wen, G. P., Platzer, M., & Hui, D. Q. (2004). Unprecedented diversity of catalytic domains in the first four modules of the putative pederin polyketide synthase. Chembiochem, 5(1), 93-98. doi:10.1002/cbic.200300782.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0012-A291-B
Abstract
Polyketides of the pederin group are highly potent antitumor compounds found in terrestrial beetles and marine sponges. Pederin is used by beetles of the general Paederus and Paederidus as a chemical defense. We have recently identified a group of putat