Expression pattern of the repulsive guidance molecules RGM A, B and C during 
mouse development.

Oldekamp, J.; Kraemer, N.; Alvarez-Bolado, G.; Skutella, T.

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Expression pattern of the repulsive guidance molecules RGM A, B and C during mouse development.

MPS-Authors

/persons/resource/persons14773

Alvarez-Bolado, G.
Department of Genes and Behavior, MPI for biophysical chemistry, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Oldekamp, J., Kraemer, N., Alvarez-Bolado, G., & Skutella, T. (2004). Expression pattern of the repulsive guidance molecules RGM A, B and C during mouse development. Gene Expression Patterns, 4(3), 283-288. Retrieved from http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6W8W-4BFP88S-2-1&_cdi=6665&_user=38661&_orig=search&_coverDate=05%2F31%2F2004&_sk=999959996&view=c&wchp=dGLbVzz-zSkWz&md5=df810543aa763d5c965984292997864a&ie=/sdarticle.pdf.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0012-ED99-3

Abstract

We have characterized for the first time the mouse expression patterns of the three known members of the novel RGM gene family ('Repulsive Axonal Guidance molecules' A, B and C) by in situ hybridization. Both RGM A and B are mostly expressed in central nervous system, while RGM C is exclusively expressed in all striated muscle and in the myocardium. RGM A and B appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGM A appears in the neuroepithelium, and only RGM B in the peripheral nervous system. During development, both RGM A and B appear also in lung and in limb cartilage, while RGM B has additional expression domains in pancreas.