English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Membrane fusion

MPS-Authors
/persons/resource/persons15266

Jahn,  R.
Department of Neurobiology, MPI for biophysical chemistry, Max Planck Society;

/persons/resource/persons15417

Lang,  T.
Department of Neurobiology, MPI for biophysical chemistry, Max Planck Society;

External Resource
No external resources are shared
Fulltext (public)

20761.pdf
(Publisher version), 0B

Supplementary Material (public)
There is no public supplementary material available
Citation

Jahn, R., Lang, T., & Suedhof, T. C. (2003). Membrane fusion. Cell, 112(4), 519-533. Retrieved from http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WSN-4811J61-B-1&_cdi=7051&_user=38661&_pii=S0092867403001120&_orig=search&_coverDate=02%2F21%2F2003&_sk=998879995&view=c&wchp=dGLbVzb-zSkzS&md5=337489ca709af930fe7d394087229959&ie=/sdarticle.pdf.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0012-F179-1
Abstract
Membrane fusion, one of the most fundamental processes in life, occurs when two separate lipid membranes merge into a single continuous bilayer. Fusion reactions share common features, but are catalyzed by diverse proteins. These proteins mediate the initial recognition of the membranes that are destined for fusion and pull the membranes close together to destabilize the lipid/water interface and to initiate mixing of the lipids. A single fusion protein may do everything or assemblies of protein complexes may be required for intracellular fusion reactions to guarantee rigorous regulation in space and time. Cellular fusion machines are adapted to fit the needs of different reactions but operate by similar principles in order to achieve merging of the bilayers.