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Cortical reafferentation following left subcortical hemorrhage: A serial functional MR study

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Hund-Georgiadis,  Margret
MPI of Cognitive Neuroscience (Leipzig, -2003), The Prior Institutes, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Lex,  Ulrike
MPI of Cognitive Neuroscience (Leipzig, -2003), The Prior Institutes, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Norris,  David G.
MPI of Cognitive Neuroscience (Leipzig, -2003), The Prior Institutes, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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von Cramon,  D. Yves
MPI of Cognitive Neuroscience (Leipzig, -2003), The Prior Institutes, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Citation

Hund-Georgiadis, M., Lex, U., Norris, D. G., & von Cramon, D. Y. (2000). Cortical reafferentation following left subcortical hemorrhage: A serial functional MR study. Neurology, 55(8), 1227-1230. doi:10.​1212/​WNL.​55.​8.​1227.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0010-A6C1-D
Abstract
A 48-year-old patient who had aphasia due to a left subcortical hemorrhage underwent three follow-up examinations to assess MR signal changes accompanying recovery. A word classification task was applied. During the 6-month follow-up period, we observed a dynamic change from negative toward positive blood oxygenation level–dependent MR signals, i.e., task-related reafferentation of eloquent cortices occurred. Clinical improvement from aphasia paralleled the MR signal changes.