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Journal Article

Statistical analysis of multi-subject fMRI data: Assessment of focal activations


Bosch,  Volker
MPI of Cognitive Neuroscience (Leipzig, -2003), The Prior Institutes, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Bosch, V. (2000). Statistical analysis of multi-subject fMRI data: Assessment of focal activations. Journal of Magnetic Resonance Imaging, 11(1), 61-64. doi:10.1002/(SICI)1522-2586(200001)11:1<61:AID-JMRI9>3.0.CO;2-C.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0010-DBF9-8
A simple procedure for analyzing multi-subject functional magnetic resonance imaging (fMRI) data is proposed. In the first step, a voxel-wise t-test across standardized z-maps is performed to identify areas that are consistently activated across subjects. In the second step, for each area, individual mean z-scores are calculated and subsequently subjected to an analysis of variance. An example is provided.