date: 2013-02-26T13:20:58Z
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pdf:docinfo:title: Identification of Alternaria alternata Mycotoxins by 
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subject: This present work describes the application of liquid chromatograpy-solid phase extraction-nuclear magnetic resonance spectroscopy to analyse Alternaria alternata crude extracts. Altenusin (1), alternariol (2), 3'-hydroxyalternariol monomethyl ether (3), and alternariol monomethyl ether (4), were separated and identified. High-resolution mass spectrometry confirmed the proposed structures. The cytotoxic effects of these compounds towards plants were determined using soybean (Glycine max) cell cultures as a model. EC50 values which range from 0.11 (±0.02) to 4.69 (±0.47) ?M showed the high cytotoxicity of these compounds.
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dc:title: Identification of Alternaria alternata Mycotoxins by 
modified: 2013-02-26T13:20:58Z
cp:subject: This present work describes the application of liquid chromatograpy-solid phase extraction-nuclear magnetic resonance spectroscopy to analyse Alternaria alternata crude extracts. Altenusin (1), alternariol (2), 3'-hydroxyalternariol monomethyl ether (3), and alternariol monomethyl ether (4), were separated and identified. High-resolution mass spectrometry confirmed the proposed structures. The cytotoxic effects of these compounds towards plants were determined using soybean (Glycine max) cell cultures as a model. EC50 values which range from 0.11 (±0.02) to 4.69 (±0.47) ?M showed the high cytotoxicity of these compounds.
pdf:docinfo:subject: This present work describes the application of liquid chromatograpy-solid phase extraction-nuclear magnetic resonance spectroscopy to analyse Alternaria alternata crude extracts. Altenusin (1), alternariol (2), 3'-hydroxyalternariol monomethyl ether (3), and alternariol monomethyl ether (4), were separated and identified. High-resolution mass spectrometry confirmed the proposed structures. The cytotoxic effects of these compounds towards plants were determined using soybean (Glycine max) cell cultures as a model. EC50 values which range from 0.11 (±0.02) to 4.69 (±0.47) ?M showed the high cytotoxicity of these compounds.
pdf:docinfo:creator: Gezimar D. de Souza 1,2,3,*, Axel Mithöfer 2, Cristina Daolio 4,5, Bernd Schneider 4 and
meta:author: Gezimar D. de Souza 1,2,3,*, Axel Mithöfer 2, Cristina Daolio 4,5, Bernd Schneider 4 and
meta:creation-date: 2013-02-26T07:23:25Z
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Author: Gezimar D. de Souza 1,2,3,*, Axel Mithöfer 2, Cristina Daolio 4,5, Bernd Schneider 4 and
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dc:description: This present work describes the application of liquid chromatograpy-solid phase extraction-nuclear magnetic resonance spectroscopy to analyse Alternaria alternata crude extracts. Altenusin (1), alternariol (2), 3'-hydroxyalternariol monomethyl ether (3), and alternariol monomethyl ether (4), were separated and identified. High-resolution mass spectrometry confirmed the proposed structures. The cytotoxic effects of these compounds towards plants were determined using soybean (Glycine max) cell cultures as a model. EC50 values which range from 0.11 (±0.02) to 4.69 (±0.47) ?M showed the high cytotoxicity of these compounds.
Keywords: LC-NMR; LC-SPE-NMR; mass spectrometry; alternariol; Alternaria; soybean; Glycine max; cell cultures; cytotoxicity
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dc:creator: Gezimar D. de Souza 1,2,3,*, Axel Mithöfer 2, Cristina Daolio 4,5, Bernd Schneider 4 and
description: This present work describes the application of liquid chromatograpy-solid phase extraction-nuclear magnetic resonance spectroscopy to analyse Alternaria alternata crude extracts. Altenusin (1), alternariol (2), 3'-hydroxyalternariol monomethyl ether (3), and alternariol monomethyl ether (4), were separated and identified. High-resolution mass spectrometry confirmed the proposed structures. The cytotoxic effects of these compounds towards plants were determined using soybean (Glycine max) cell cultures as a model. EC50 values which range from 0.11 (±0.02) to 4.69 (±0.47) ?M showed the high cytotoxicity of these compounds.
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title: Identification of Alternaria alternata Mycotoxins by 
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pdf:docinfo:keywords: LC-NMR; LC-SPE-NMR; mass spectrometry; alternariol; Alternaria; soybean; Glycine max; cell cultures; cytotoxicity
pdf:docinfo:modified: 2013-02-26T13:20:58Z
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creator: Gezimar D. de Souza 1,2,3,*, Axel Mithöfer 2, Cristina Daolio 4,5, Bernd Schneider 4 and
dc:subject: LC-NMR; LC-SPE-NMR; mass spectrometry; alternariol; Alternaria; soybean; Glycine max; cell cultures; cytotoxicity
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meta:keyword: LC-NMR; LC-SPE-NMR; mass spectrometry; alternariol; Alternaria; soybean; Glycine max; cell cultures; cytotoxicity
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pdf:docinfo:created: 2013-02-26T07:23:25Z