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dc:title: Figure S5
modified: 2009-09-07T21:15:01
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dc:description: <p>Schematic model of Rab regulated Golgi fragmentation and <italic>Chlamydia</italic> development. Under normal cellular conditions Golgi matrix proteins, including golgin-84, stabilize the GA, whereas Rab6 and Rab11 stimulate GA fragmentation. Upon infection, <italic>Chlamydia</italic> can influence these factors, either positively or negatively, to ensure efficient development. In this model <italic>C. trachomatis</italic> targets golgin-84, Rab6 and/or Rab11 to destabilize Golgi structure and stimulate ceramide acquisition, thus enhancing the development of infectious particles.</p>
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description: <p>Schematic model of Rab regulated Golgi fragmentation and <italic>Chlamydia</italic> development. Under normal cellular conditions Golgi matrix proteins, including golgin-84, stabilize the GA, whereas Rab6 and Rab11 stimulate GA fragmentation. Upon infection, <italic>Chlamydia</italic> can influence these factors, either positively or negatively, to ensure efficient development. In this model <italic>C. trachomatis</italic> targets golgin-84, Rab6 and/or Rab11 to destabilize Golgi structure and stimulate ceramide acquisition, thus enhancing the development of infectious particles.</p>
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dcterms:created: 2009-09-07T21:15:01
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title: Figure S5
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