Content-Style-Type: text/css X-Parsed-By: org.apache.tika.parser.DefaultParser dc.Type: research-article dc.Title: Integrated Measurement of the Mass and Surface Charge of Discrete Microparticles Using a Suspended Microchannel Resonator title: Analytical Chemistry - (ACS Publications) dc.Identifier: 10.1021/ac9005149 dc.Publisher: American Chemical Society dc.Language: EN fb:app_id: 121948137886736 dc.Description: Measurements of the mass and surface charge of microparticles are employed in the characterization of many types of colloidal dispersions. The suspended microchannel resonator (SMR) is capable of measuring individual particle masses with femtogram resolution. Here, we employ the high sensitivity of the SMR resonance frequency to changes in particle position, relative to the cantilever tip, to determine the electrophoretic mobility of discrete particles in an applied electric field. When a sinusoidal electric field is applied to the suspended microchannel, the transient resonance frequency shift corresponding to a particle transit can be analyzed by digital signal processing to extract both the buoyant mass and electrophoretic mobility of each particle. These parameters, together with the mean particle density, can be used to compute the size, absolute mass, and surface charge of discrete microspheres, leading to a true representation of the mean and polydispersity of these quantities for a population. We ... dc.Format: text/HTML dc:title: Analytical Chemistry - (ACS Publications) Content-Encoding: UTF-8 Content-Type-Hint: text/html; charset=UTF-8 dc.Creator: Philip Dextras dc.Date: May 8, 2009 imagetoolbar: no robots: noarchive,noindex,nofollow dc.Coverage: world Content-Type: text/html; charset=UTF-8 MSSmartTagsPreventParsing: true