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  Elevated GH/IGF-I, due to somatotrope-specific loss of both IGF-I and insulin receptors, alters glucose homeostasis and insulin sensitivity in a diet-dependent manner

Gahete, M. D., Cordoba-Chacon, J., Anadumaka, C. V., Brüning, J. C., Kahn, C. R., Luque, R. M., et al. (2011). Elevated GH/IGF-I, due to somatotrope-specific loss of both IGF-I and insulin receptors, alters glucose homeostasis and insulin sensitivity in a diet-dependent manner. Endocrinology, 152(12), 4825-4837. doi:10.1210/en.2011-1447.

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 Creators:
Gahete, Manuel D.1, Author
Cordoba-Chacon, Jose1, Author
Anadumaka, Chike V.1, Author
Brüning, Jens Claus2, Author           
Kahn, C. Ronald1, Author
Luque, Raul M.1, Author
Kineman, Rhonda D.1, Author
Affiliations:
1a Jesse Brown Veterans Affairs Medical Center, Research and Development Division, Building 11A, 820 South Damen Avenue, Chicago, IL 60612, United States b Section of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, United States c Center for Endocrinology, Diabetes and Preventive Medicine, University Hospital, 50924 Köln, Germany d Section of Obesity and Hormone Action, Joslin Diabetes Center, Boston, MA 02215, United States e Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Instituto Maimonides de Investigacion Biomedica de Cordoba (IMIBIC), 14014 Cordoba, Spain f Centro de Investigacion Biomedica en Red de la Fisiopatologia de la Obesidad y Nutricion (CIBERobn), 14014 Cordoba, Spain, ou_persistent22              
2Brüning – Neuronal Control of Metabolism, Department Brüning, Max Planck Institute for Metabolism Research, Max Planck Society, ou_2149644              

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 Abstract: Copyright © 2011 by The Endocrine Society.

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Language(s): eng - English
 Dates: 2011
 Publication Status: Issued
 Pages: -
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 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 575646
DOI: 10.1210/en.2011-1447
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Title: Endocrinology
Source Genre: Journal
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Pages: - Volume / Issue: 152 (12) Sequence Number: - Start / End Page: 4825 - 4837 Identifier: ISSN: 00137227