The Organocatalytic Asymmetric Prins Cyclization.

Tsui, Garvin Chit; Liu, Luping; List, Benjamin

doi:10.1002/anie.201500219

アイテム詳細

登録内容を編集ファイル形式で保存

一時保存へ追加

タグ情報を表示リリース履歴を表示詳細要約

公開

学術論文

The Organocatalytic Asymmetric Prins Cyclization.

MPS-Authors

/persons/resource/persons180745

Tsui, Garvin Chit
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons180741

Liu, Luping
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58764

List, Benjamin
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

External Resource

There are no locators available

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

フルテキスト (公開)

公開されているフルテキストはありません

付随資料 (公開)

There is no public supplementary material available

引用

Tsui, G. C., Liu, L., & List, B. (2015). The Organocatalytic Asymmetric Prins Cyclization. Angewandte Chemie International Edition, 54(26), 7703-7706. doi:10.1002/anie.201500219.

引用: https://hdl.handle.net/11858/00-001M-0000-0028-30E4-9

要旨

We describe here the design and development of an organocatalytic Prins cyclization. In the presence of a confined chiral imidodiphosphoric acid catalyst, salicylaldehydes react with 3-methyl-3-buten-1-ol to afford highly functionalized 4-methylenetetrahydropyrans in excellent regio- and enantioselectivity. The extreme steric demand of the acid catalyst is key for the success of this transformation.