%PDF-1.4
%
121 0 obj
<>
endobj
120 0 obj
<>stream
2016-01-05T03:51:23-08:00
XPP
2015-11-03T17:36:44Z
2016-01-05T03:51:23-08:00
application/pdf
uuid:f63d4b7b-1dd1-11b2-0a00-7d08273d2300
uuid:f63d4b7e-1dd1-11b2-0a00-1e0000000000
endstream
endobj
118 0 obj
<>
endobj
114 0 obj
<>
endobj
115 0 obj
<>
endobj
116 0 obj
<>
endobj
91 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[9 9 603 792]/Type/Page>>
endobj
97 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[9 9 603 792]/Type/Page>>
endobj
202 0 obj
<>/ProcSet[/PDF/Text/ImageC]/XObject<>>>/Type/Page>>
endobj
212 0 obj
[221 0 R 222 0 R 223 0 R 224 0 R 225 0 R 226 0 R 227 0 R 228 0 R 229 0 R 230 0 R]
endobj
213 0 obj
<>stream
q
600 0 0 137.5 6 654.5 cm
/Im0 Do
Q
BT
/T1_0 1 Tf
12 0 0 12 98 523.99973 Tm
(Markus Zweckstetter and Joshua Salafsky)Tj
0 1 TD
(Giller, Stefan Becker, Tiago F. Outeiro,)Tj
0 1.00001 TD
(Francesca Munari, Timo Stroh\344ker, Karin )Tj
0 1 TD
(Ben Moree, Guowei Yin, Diana F. L\341zaro,)Tj
T*
(\240 )Tj
/T1_1 1 Tf
T*
(and Reduce Its Aggregation in Cells)Tj
13.46196 1.00001 Td
(-Synuclein)Tj
/T1_2 1 Tf
-0.631 0 Td
(a)Tj
/T1_1 1 Tf
-12.83096 0 Td
(Conformation of Monomeric )Tj
17.41597 1 Td
(the)Tj
-17.41597 0 Td
(Second-Harmonic Generation Modulate )Tj
T*
(Small Molecules Detected by)Tj
1 0 0 rg
/T1_3 1 Tf
T*
(Molecular Biophysics:)Tj
ET
0.80392 0.78824 0.78824 rg
343 585 212 59 re
0 0 m
f
343 585 212 59 re
0 0 m
S
0.41176 0.41176 0.41176 rg
348 617 202 22 re
0 0 m
f
q
200 0 0 20 349 618 cm
-1 TL /Im1 Do
Q
348 590 202 22 re
0 0 m
f
q
200 0 0 20 349 591 cm
-1 TL /Im2 Do
Q
BT
0 g
/T1_4 1 Tf
10 0 0 10 98 503.99997 Tm
(doi: 10.1074/jbc.M114.636027 originally published online September 22, 2\
015)Tj
6.50199 1 Td
(2015, 290:27582-27593.)Tj
-6.50199 0 Td
(J. Biol. Chem.\240)Tj
ET
98 480 m
519 480 l
0 0 m
S
BT
ET
BT
/T1_0 1 Tf
10 0 0 10 98 435.99997 Tm
(\240 )Tj
/T1_3 1 Tf
35.46296 1 Td
( )Tj
0 0 1 rg
-11.56299 0 Td
(10.1074/jbc.M114.636027)Tj
0 g
-23.89997 0 Td
(Access the most updated version of this article at doi: )Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 98 410.99997 Tm
(\240 )Tj
/T1_3 1 Tf
41.06696 1 Td
(.)Tj
0 0 1 rg
-7.66902 0 Td
(JBC Affinity Sites)Tj
0 g
-33.39794 0 Td
(Find articles, minireviews, Reflections and Classics on similar topics o\
n the )Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 129.11993 396 Tm
(\240)Tj
/T1_3 1 Tf
-3.11199 0 Td
(Alerts: )Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 118 365.99994 Tm
(\240 )Tj
/T1_3 1 Tf
19.52397 1 Td
( )Tj
0 0 1 rg
-18.61797 0 Td
(When a correction for this article is posted)Tj
0 g
-0.906 0 Td
(\225\240 )Tj
11.68699 1.00001 Td
( )Tj
0 0 1 rg
-10.78099 0 Td
(When this article is cited)Tj
0 g
-0.906 0 Td
(\225\240 )Tj
ET
BT
/T1_3 1 Tf
10 0 0 10 142.44986 351 Tm
( to choose from all of JBC's e-mail alerts)Tj
0 0 1 rg
-4.44499 0 Td
(Click here)Tj
ET
BT
0 g
/T1_0 1 Tf
10 0 0 10 98 305.99994 Tm
(\240 )Tj
/T1_3 1 Tf
25.78895 1 Td
( )Tj
0 0 1 rg
-25.78895 0 Td
(http://www.jbc.org/content/290/46/27582.full.html#ref-list-1)Tj
0 g
0 1.00001 TD
(This article cites 58 references, 17 of which can be accessed free at)Tj
ET
BT
/T1_0 1 Tf
0 -8 8 0 587 512.27625 Tm
( at Max Planck Inst.Biophysikalische Chemie,Otto Hahn Bibl,Pf.2841,37018\
Goettingen on January 5, 2016)Tj
0 0 1 rg
-7.88899 0 Td
(http://www.jbc.org/)Tj
0 g
-7.55399 0 Td
(Downloaded from )Tj
ET
endstream
endobj
218 0 obj
<>/Filter/FlateDecode/Height 275/Length 466992/Name/X/Subtype/Image/Type/XObject/Width 1200>>stream
HW[G[_ggfgǗ8*eQ,E ,?ƃx<.nC`76xggꚙצjUWW:uws1Few&?m̈́Fy_3H_c@Ii[=)vF#l,:20)N44Ù6џԇ"%QwBфrzzEPN?[_xGﻷf$_<1yS#=㾶dΚ>
A#X-}
)!J2Cpc\ S6$@RJ
08%`G
5ă
dzxښ}hU,̘{jw@Tv3 h=i_q@\)h^
!j'a ԴC]]fdm
n5Rj=-q9V١٭|nM1jc
BVAFhs!W3Jc$ #Г!9$I `lʆ
aBr["HFy3?V[w!1)C)-,qJ#kdJsɇP۬U7.]y=J4[6I8Bhbl
CL=0;)T
)ʀ;{ zAa&n=`(MfzX"aNF.b~!/5iC\[
q
i֖>{Vmar{2.P@`!KXH0 #p௬_HDq8Ns K@oBay5d&TqSl5Б̆;O9jԨmA:Z
U^fcRct=91rsØi2
8B\M@w/ |nTX?xbM\g5^\
:8!ap;]?Yh?hQAZzA8GCԶt~ou фI+Z`Q[@DP Q1\̢PIauHNpHW!Ī: qh`}`)
Vs%bV]?+֓C6QË,ME-uBC@NHt6dԁ;e k58&2A0+|`z9d"7:斘Fɺ[Ln%[1 #% Y%'K[|FW
e WNX)] "Zf̼x4.;G4
\-aJܞNp|O7uuEXE
M @:1-5WXj)d[