Back to the beginning - the quest for thymic epithelial stem cells

Swann, Jeremy; Boehm, Thomas

doi:10.1002/eji.200737709

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Back to the beginning - the quest for thymic epithelial stem cells

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Swann, Jeremy
Department of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society;

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Boehm, Thomas
Department of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society;

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https://onlinelibrary.wiley.com/doi/10.1002/eji.200737709
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引用

Swann, J., & Boehm, T. (2007). Back to the beginning - the quest for thymic epithelial stem cells. European Journal of Immunology, 37, 2364-2366. doi:10.1002/eji.200737709.

引用: https://hdl.handle.net/11858/00-001M-0000-002B-91F8-4

要旨

Stem cell-based therapies hold much promise for the rejuvenation of aged or damaged tissues; however, before such cells can be used therapeutically, they must first be accurately identified. In this issue of the European Journal of Immunology it is reported that MTS24, a marker previously associated with progenitor cells of the thymic epithelium, fails to accurately identify epithelial cell populations with the ability to reconstitute a functional thymus. This finding demonstrates that much progress needs to be made before thymic epithelial stem cells can be harnessed for clincal benefit.