Insights into the molecular basis for substrate binding and specificity of the wild-type L-arginine/agmatine antiporter AdiC
- Hüseyin Ilgüa,b1,
- Jean-Marc Jeckelmanna,b1,
- Vytautas Gapsysc,
- Zöhre Ucuruma,b,
- Bert L. de Grootc, and
- Dimitrios Fotiadisa,b,2
- aInstitute of Biochemistry and Molecular Medicine, University of Bern, CH-3012 Bern, Switzerland;
- bSwiss National Centre of Competence in Research TransCure, University of Bern, CH-3012 Bern, Switzerland;
- cComputational Biomolecular Dynamics Group, Max-Planck-Institute for Biophysical Chemistry, D-37077 Goettingen, Germany
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Edited by Christopher Miller, Howard Hughes Medical Institute, Brandeis University, Waltham, MA, and approved July 26, 2016 (received for review April 4, 2016)