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Patent

Vaccine against carbapenem-resistant klebsiella pneumoniae

MPG-Autoren
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Seeberger,  Peter H.
Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Pereira,  Claney Lebev
Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Xiao,  Guozhi
Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Khan,  Naeem
Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Chakkumkal,  Anish
Chakkumal Anish, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Zitation

Seeberger, P. H., Pereira, C. L., Xiao, G., Khan, N., & Chakkumkal, A.(2016). Vaccine against carbapenem-resistant klebsiella pneumoniae.


Zitierlink: https://hdl.handle.net/11858/00-001M-0000-002C-038D-9
Zusammenfassung
The present invention relates to synthetic saccharides of general fornnula (I): V*−[Ux+2−Ux+ 1−Ux]n−V−O−L−NH2 that are related to carbapenem-resistant Kliebsella pneumoniae capsular polysaccharide and conjugates thereof. Said conjugates and pharmaceutical composition containing said conjugates are useful for prevention and/or treatment of diseases associated with carbapenem-resistant Klebsiella pneumoniae. Furthermore, the synthetic saccharides of general formula (I): V*−[Ux+2−Ux+1−Ux]n−V−O−L−NH2 are useful as marker in immunological assays for detection of antibodies against carbapenem-resistant Klebsiella pneumoniae bacteria.