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citation_reference: citation_title=Polyspermy in in vitro fertilization of human oocytes: frequency and possible causes; citation_author=H. H. van der Ven; citation_journal_title=Ann. NY Acad. Sci.; citation_volume=442; citation_pages=88-95; citation_publication_date=1985
citation_journal_title: Nature Communications
dc.rights: © 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.
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og:description: Mammalian eggs release cortical granules to avoid being fertilized by more than a single sperm as polyspermy results in nonviable embryos. Here, the authors describe the mechanism driving translocation of the granules to the cortex in the mouse egg and show this process is essential to prevent polyspermy.
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dc:title: Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes : Nature Communications
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citation_author: Liam P. Cheeseman
WT.z_subject_term: Actin;Motor proteins;Reproductive biology;Secretion
dc.date: 2016-12-19
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citation_doi: doi:10.1038/ncomms13726
dc.title: Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes
citation_volume: 7
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dc.dateSubmitted: 2016-06-12
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citation_title: Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes
citation_author_institution: Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK
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citation_publisher: Nature Publishing Group
dc.dateAccepted: 2016-10-27
description: Mammalian eggs release cortical granules to avoid being fertilized by more than a single sperm as polyspermy results in nonviable embryos.
title: Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes : Nature Communications
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dc.source: Nature Communications, Published online: 19 December 2016; | doi:10.1038/ncomms13726
dc.creator: Liam P. Cheeseman
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twitter:title: Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes
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twitter:description: Mammalian eggs release cortical granules to avoid being fertilized by more than a single sperm as polyspermy results in nonviable embryos. Here, the authors describe the mechanism driving translocation of the granules to the cortex in the mouse egg and show this process is essential to prevent polyspermy.
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