Biological underpinnings of different MR contrasts in the human midbrain using 
quantitative structural MR imaging at 9.4T: Validation with 14T ex-vivo 
measurements and PLI

Loureiro, J; Hagberg, G; Tuzzi, E; Pohmann, R; Schickardt, Z; Himmelbach, M; Ethofer, T; Valverde, M; Grodd, W; Scheffler, K

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Biological underpinnings of different MR contrasts in the human midbrain using quantitative structural MR imaging at 9.4T: Validation with 14T ex-vivo measurements and PLI

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Loureiro, J
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons83952

Hagberg, G
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons214563

Tuzzi, E
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons84145

Pohmann, R
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons216525

Schickardt, Z
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons84271

Valverde, M
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons192649

Grodd, W
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons84187

Scheffler, K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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引用

Loureiro, J., Hagberg, G., Tuzzi, E., Pohmann, R., Schickardt, Z., Himmelbach, M., Ethofer, T., Valverde, M., Grodd, W., & Scheffler, K. (2017). Biological underpinnings of different MR contrasts in the human midbrain using quantitative structural MR imaging at 9.4T: Validation with 14T ex-vivo measurements and PLI. Poster presented at 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017), Honolulu, HI, USA.

引用: https://hdl.handle.net/21.11116/0000-0000-C4D5-2

要旨

In this study we use relaxometry and susceptibility mapping to obtain enhanced contrast in the midbrain, in particular in the superior colliculus (SC). High resolution GRE images were obtained in 11 subjects at 9.4T. We calculated CNR values for each contrast for three midbrain regions (superior colliculus,red nucleus and aqueductal gray). were were obtained across 11 subjects in individual and MNI space. These measurement were validated with ex-vivo measurements in the 9.4T, 14.1T and PLI imaging.