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Molecular mechanism of fusion pore formation driven by the neuronal SNARE complex
Satyan Sharma and Manfred Lindau
Satyan Sharma
aLaboratory for Nanoscale Cell Biology, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany
Manfred Lindau
aLaboratory for Nanoscale Cell Biology, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, GermanybSchool of Applied and Engineering Physics, Cornell University, Ithaca, NY 14850
Edited by Axel T. Brunger, Stanford University, Stanford, CA, and approved November 1, 2018 (received for review October 2, 2018)
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- Download Movie_S01 (AVI) - Fusion pore formation between a nanodisc and a bilayer. Coarse-grained simulation trajectory (Sim1, 2.1 μs) of membrane fusion, pore formation and its subsequent closure. Water density at the fusion site is shown as cyan surface.
Molecular mechanism of fusion pore formation driven by the neuronal SNARE complex
Satyan Sharma, Manfred Lindau
Proceedings of the National Academy of Sciences Nov 2018, 201816495; DOI: 10.1073/pnas.1816495115
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