日本語
 
Help Privacy Policy ポリシー/免責事項
  詳細検索ブラウズ

アイテム詳細


公開

報告書

Genetic diversity of HLA system in two populations from Sinaloa, Mexico: Culiacán and rural Sinaloa

MPS-Authors
/persons/resource/persons202721

Clayton,  Stephen
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society;

/persons/resource/persons214002

Barquera,  Rodrigo
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society;

External Resource
There are no locators available
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
フルテキスト (公開)
公開されているフルテキストはありません
付随資料 (公開)
There is no public supplementary material available
引用

Clayton, S., Barquera, R., Uribe-Duarte, M. G., Vázquez, I. G., Zúñiga, J., Arrieta-Bolaños, E., Hernández-Zaragoza, D. I., de Ruíz-Corral, M. J., Escobedo-Ruíz, A., Arellano-Prado, F. P., García-Arias, V. E., Rodríguez-López, M. E., Bravo-Acevedo, A., de Sánchez-Fernández, M. G. J., Aguilar-Campos, J. A., Serrano-Osuna, R., Gómez-Navarro, B., Sandoval-Sandoval, M. J., Yunis, E. J., Bekker-Méndez, C., & Granados, J.(2020). Genetic diversity of HLA system in two populations from Sinaloa, Mexico: Culiacán and rural Sinaloa (shh2249).


引用: https://hdl.handle.net/21.11116/0000-0003-C3D9-C
要旨
We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 286 Mexicans from the state of Sinaloa living in Culiacán (N = 103) and rural communities (N = 183) to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes for the state of Sinaloa include ten Native American most probable ancestry and five European most probable ancestry haplotypes. The admixture estimates revealed that the main genetic components in the state of Sinaloa are European (62.39 ± 3.47) and Native American (37.61 ± 2.85), while the African genetic component was estimated as virtually absent (0.00 ± 1.86).